Nad-Dependent Deacetylase Sirtuin-5

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-64   SER-65  4.6 4.6 1.7 0.3 91.1 89.3 14.4
 SER-65   GLY-66  1.8 1.7 1.0 18.4 89.9 87.9 -36.4
 GLY-66   VAL-67  5.6 5.4 -19.0 2.9 24.4 24.0 129.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-107   VAL-108  12.6 12.7 4.6 -7.2 143.6 147.3 -9.8
 GLY-110   SER-111  10.1 9.9 -3.6 -17.4 8.8 22.4 98.0
 SER-111   LYS-112  9.5 9.3 19.1 12.2 108.9 106.9 -79.1
 LYS-112   GLU-113  5.6 5.5 4.9 -11.0 94.6 89.8 -6.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-157   HIS-158  5.3 5.4 2.5 -5.9 102.3 104.5 3.4
 HIS-158   GLY-159  3.1 3.3 0.2 3.6 91.0 90.2 -4.2
 GLY-159   SER-160  0.8 0.5 -0.3 13.1 158.7 155.4 65.8
 SER-160   LEU-161  3.3 3.1 0.4 -5.0 89.5 81.6 50.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-226   LEU-227  7.0 7.4 -13.8 5.4 54.8 54.9 34.7
 LEU-227   ASP-228  5.6 5.9 3.3 7.6 49.5 47.6 59.0
 ASP-228   PRO-229  4.3 4.5 7.2 -4.3 77.8 73.6 -10.8
 PRO-229   ALA-230  7.6 7.6 0.5 -5.0 108.5 110.1 38.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees