Dual Specificity Mitogen-Activated Protein Kinase Kinase 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-76   GLU-77  10.3 10.2 34.0 -26.3 61.9 49.5 87.2
 GLU-77   LEU-78  9.7 9.3 -22.5 24.7 139.8 139.1 25.5
 LEU-78   GLY-79  7.1 7.0 0.3 13.5 26.3 24.5 75.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-97   MET-98  5.9 6.3 24.5 -28.4 132.6 133.0 -8.0
 MET-98   ALA-99  3.1 3.5 1.0 -9.5 127.8 128.5 44.9
 ALA-99   ARG-100  0.8 1.1 -5.0 1.8 103.7 101.2 10.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees