Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-713   LYS-714  6.1 6.0 10.2 -0.7 147.4 146.3 -44.1
 LYS-714   GLY-715  6.8 6.7 -11.6 -5.0 67.5 70.2 57.8
 GLY-715   PRO-716  3.7 3.7 13.0 -17.9 109.5 122.5 27.1
 PRO-716   GLU-717  5.2 5.4 -91.4 83.9 30.0 27.2 53.4
 GLU-717   ILE-718  7.6 6.8 0.8 2.9 109.3 108.9 14.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-816   LEU-817  11.7 11.6 -2.2 6.5 54.7 43.0 18.8
 LEU-817   PRO-818  9.4 9.6 -0.1 -4.3 40.0 46.6 31.8
 PRO-818   ALA-819  8.1 8.1 -13.4 0.0 98.5 98.9 5.5
 ALA-819   VAL-820  5.1 4.9 7.1 -9.2 101.5 125.4 -5.4
 VAL-820   SER-821  3.9 4.1 -32.3 -6.1 90.1 75.3 56.7
 SER-821   GLU-822  6.9 7.3 -1.2 7.3 22.7 27.9 -21.7
 GLU-822   LYS-823  9.0 9.3 -1.4 0.2 84.0 92.0 -14.0
 LYS-823   ASP-824  9.1 9.4 -3.3 -6.8 76.8 82.2 26.2
 ASP-824   ILE-825  5.6 5.8 18.9 -13.8 166.6 164.4 -8.5
 ILE-825   GLN-826  4.9 5.2 -1.4 4.0 61.5 60.9 -16.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees