Erythropoietin Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-119   LEU-120  3.3 3.2 4.8 -11.4 152.7 157.9 32.2
 LEU-120   LEU-121  2.4 2.4 -26.8 29.4 75.4 74.0 -20.4
 LEU-121   ASP-122  1.9 2.4 -14.8 3.9 13.5 14.9 51.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-155   TYR-156  9.3 9.4 3.4 -1.6 2.0 7.6 -6.5
 TYR-156   GLU-157  10.7 10.7 8.3 -2.2 67.6 64.2 9.1
 GLU-157   VAL-158  12.4 12.0 -0.3 3.2 156.6 150.0 32.9
 VAL-158   ASP-159  14.1 14.3 -12.3 1.2 126.8 131.7 -26.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-169   GLN-170  19.2 17.1 -161.7 119.1 44.3 12.0 237.6
 GLN-170   ARG-171  19.9 19.0 29.2 -22.5 127.6 130.0 -40.4
 ARG-171   VAL-172  17.5 16.9 16.4 -4.8 148.1 152.4 -57.7
 VAL-172   GLU-173  17.7 17.7 5.1 27.3 128.4 128.4 -114.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-204   PHE-205  3.2 3.2 -26.9 36.7 143.7 142.2 42.0
 PHE-205   GLY-206  3.0 2.5 -18.0 22.1 123.5 120.1 19.4
 GLY-206   GLY-207  5.2 5.0 -5.9 10.1 145.1 146.7 27.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-208   TRP-209  6.1 5.3 -5.7 -1.0 60.8 63.1 30.3
 TRP-209   SER-210  5.9 5.2 -5.3 -1.6 50.4 49.6 30.9
 SER-210   GLU-211  2.9 2.4 -6.7 1.8 19.0 20.2 11.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees