Mu-Like Calpain

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-203   PHE-204  11.0 15.4 70.0 -44.8 110.6 131.8 -95.3
 PHE-204   GLU-205  8.2 13.0 155.3 17.2 142.7 119.7 -475.8
 GLU-205   ASP-206  6.0 11.1 -154.3 31.7 34.5 92.5 443.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-283   MET-284  15.4 14.9 14.3 -39.6 65.6 63.1 -34.4
 MET-284   ARG-285  13.9 14.0 -14.4 40.6 119.7 95.4 15.6
 ARG-285   ASN-286  15.9 16.2 -5.5 20.7 103.8 87.3 34.2
 ASN-286   PRO-287  17.1 17.1 -0.3 3.2 142.6 145.1 5.0
 PRO-287   TRP-288  18.2 18.2 -6.9 51.4 82.4 80.4 23.5
 TRP-288   GLY-289  21.0 21.4 -34.0 -11.5 56.8 100.3 6.2
 TRP-288   GLY-289  21.0 21.4 -34.0 -11.5 56.8 100.3 6.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TRP-288   GLY-289  21.0 21.4 -34.0 -11.5 56.8 100.3 6.2
 TRP-288   GLY-289  21.0 21.4 -34.0 -11.5 56.8 100.3 6.2
 GLY-289   GLU-290  22.3 22.5 65.2 -112.0 169.6 148.8 142.1
 GLU-290   VAL-291  22.6 23.3 49.2 121.9 111.1 131.3 415.4
 VAL-291   GLU-292  21.0 21.9 176.1 164.9 34.5 87.3 -40.4
 VAL-291   GLU-292  21.0 21.9 176.1 164.9 34.5 87.3 -40.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-291   GLU-292  21.0 21.9 176.1 164.9 34.5 87.3 -40.4
 VAL-291   GLU-292  21.0 21.9 176.1 164.9 34.5 87.3 -40.4
 GLU-292   TRP-293  21.1 19.6 151.0 48.2 56.2 24.2 620.6
 TRP-293   LYS-294  18.6 17.2 28.7 -47.0 45.3 55.0 -83.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-334   PHE-335  6.7 7.0 -159.8 1.6 92.1 142.6 329.4
 PHE-335   THR-336  5.0 6.2 -171.0 57.0 149.0 92.0 -238.4
 THR-336   LYS-337  3.6 4.7 122.4 32.0 46.1 35.9 467.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees