Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-209   LEU-210  8.5 9.1 12.1 -32.1 77.8 77.0 -60.5
 LEU-210   GLN-211  5.0 5.4 -0.6 -16.9 41.9 32.1 163.0
 GLN-211   ALA-212  4.2 4.1 14.7 -27.0 93.6 112.1 -29.9
 ALA-212   ARG-213  7.7 7.3 8.7 7.1 56.1 53.3 76.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-339   ILE-340  4.0 3.8 8.0 -7.7 150.5 159.6 -7.9
 ILE-340   LYS-341  2.1 1.9 -0.2 -11.0 96.1 93.7 28.9
 LYS-341   LEU-342  3.7 3.7 -46.8 28.8 21.2 22.9 128.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-474   ALA-475  9.7 9.4 -9.8 5.3 102.3 110.0 -69.5
 ALA-475   PRO-476  7.3 7.0 28.8 -11.2 102.8 109.2 -5.3
 PRO-476   GLY-477  3.8 3.8 37.1 -83.8 161.7 176.6 370.6
 GLY-477   ARG-478  1.7 2.7 5.5 19.9 102.7 96.9 -72.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees