Cytochrome P450 2B4

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-204   SER-205  6.2 5.2 -18.7 33.1 92.1 72.2 -6.6
 SER-205   PHE-206  2.6 1.9 -27.0 -175.7 157.0 135.1 167.0
 PHE-206   SER-207  2.8 0.9 -31.9 7.9 128.6 122.1 -29.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-222   PHE-223  17.7 18.3 21.1 -5.5 47.8 112.6 5.2
 PHE-223   LEU-224  16.3 15.4 22.5 2.5 74.8 45.6 25.6
 LEU-224   LYS-225  12.6 13.4 4.5 24.4 59.9 55.7 34.4
 LYS-225   HIS-226  13.0 16.2 -4.5 24.0 139.5 58.7 12.7
 HIS-226   PHE-227  16.0 17.0 37.8 20.2 41.8 97.6 14.1
 PHE-227   PRO-228  16.2 13.6 -68.3 38.4 63.9 128.2 -150.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-471   PRO-472  3.1 2.6 -5.9 -29.5 9.1 1.1 41.9
 PRO-472   ARG-473  2.8 2.1 31.4 -31.0 106.5 118.0 0.0
 ARG-473   GLU-474  5.7 4.6 -76.6 -155.2 27.5 37.9 -136.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-476   VAL-477  9.6 5.2 -120.5 101.5 108.8 59.0 35.9
 VAL-477   GLY-478  8.6 6.7 -136.8 -16.2 158.5 51.7 -107.3
 GLY-478   ASN-479  6.7 4.2 -112.2 -18.5 69.0 41.5 120.5
 ASN-479   VAL-480  3.0 2.9 -78.2 159.3 78.9 89.7 -15.6
 VAL-480   PRO-481  1.8 1.1 27.4 -4.4 161.0 149.4 -28.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees