Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-86   PRO-87  6.3 6.3 -32.3 -2.1 101.4 87.0 -14.4
 PRO-87   GLU-88  2.5 3.1 76.6 -20.5 33.1 30.6 123.8
 GLU-88   ILE-89  3.8 4.1 11.0 -3.4 94.0 97.5 10.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-181   CYS-182  8.8 9.3 23.1 0.2 33.0 23.4 56.0
 CYS-182   ASP-183  9.0 9.3 7.3 -6.0 40.9 42.4 35.7
 ASP-183   VAL-184  8.8 10.0 -27.7 47.9 126.1 135.3 11.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees