Plasminogen Activator Inhibitor-2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-123   GLU-124  15.7 17.2 21.2 -28.1 107.0 127.9 9.9
 GLU-124   SER-125  13.5 14.5 3.7 8.1 81.7 74.6 62.7
 SER-125   VAL-126  9.9 10.8 7.5 -14.6 106.3 124.3 70.0
 VAL-126   ASN-127  8.9 9.5 -9.5 48.1 95.0 104.8 71.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-133   SER-134  19.6 20.2 3.4 -17.1 58.9 61.1 -32.0
 SER-134   ALA-135  21.8 22.4 13.7 13.0 61.1 68.2 111.8
 ALA-135   SER-136  19.0 19.8 86.5 -68.5 54.3 16.8 -73.7
 SER-136   PHE-137  18.1 18.8 -24.1 -21.3 118.4 93.0 -59.4
 PHE-137   ARG-138  14.7 15.3 20.3 3.6 12.2 15.7 206.7
 ARG-138   GLU-139  14.5 14.0 -6.7 -17.1 104.6 114.5 -19.7
 GLU-139   GLU-140  14.2 12.8 6.5 6.8 71.2 81.1 58.6
 GLU-140   TYR-141  11.1 9.6 -3.2 5.2 42.8 31.6 -31.2
 TYR-141   ILE-142  9.4 8.7 -5.8 -5.6 71.8 77.7 -4.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-148   TYR-149  3.2 2.8 7.1 1.6 23.2 24.1 41.3
 TYR-149   SER-150  4.3 4.1 -4.6 1.3 105.6 96.4 59.8
 SER-150   SER-151  7.9 7.6 2.5 43.6 33.1 36.3 314.7
 SER-151   GLU-152  7.6 7.8 -132.0 151.1 74.9 91.3 -2.7
 GLU-152   PRO-153  10.1 11.3 -50.6 6.2 137.9 118.7 -272.4
 PRO-153   GLN-154  10.5 11.7 -18.1 1.6 103.7 101.7 17.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-199   ASN-200  4.8 5.3 -2.9 28.8 118.4 117.3 146.0
 ASN-200   ALA-201  3.9 5.2 21.0 6.1 134.9 137.9 -157.9
 ALA-201   VAL-202  6.7 8.4 7.4 10.4 64.5 70.1 69.8
 VAL-202   TYR-203  9.2 10.6 -0.6 -4.9 50.2 50.8 5.7
 TYR-203   PHE-204  12.7 14.1 -4.4 -0.2 116.3 106.4 -5.4
 PHE-204   LYS-205  15.6 16.9 -7.6 16.2 47.4 48.4 -36.0
 LYS-205   GLY-206  19.1 20.4 8.6 -29.7 47.5 64.9 -132.8
 GLY-206   LYS-207  21.8 23.1 -14.2 -6.5 67.5 44.4 102.6
 LYS-207   TRP-208  25.6 26.4 35.9 -6.0 81.6 83.1 26.0
 TRP-208   LYS-209  27.3 27.9 1.7 7.9 54.0 53.3 38.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-342   MET-343  12.4 12.4 -0.6 6.0 116.6 103.5 -25.9
 MET-343   SER-344  12.2 12.2 -4.0 5.0 82.7 75.7 -8.7
 SER-344   GLU-345  15.9 15.9 -13.0 2.7 69.0 68.8 -54.2
 GLU-345   ARG-346  19.1 18.3 -4.3 14.7 139.3 123.4 19.3
 ARG-346   ASN-347  20.7 21.0 -150.4 123.8 116.5 131.0 -191.7
 ASN-347   ASP-348  21.4 19.4 85.3 -37.9 24.5 24.0 400.9
 ASP-348   LEU-349  20.7 20.0 -41.6 14.6 101.4 130.7 -70.6
 LEU-349   PHE-350  16.9 16.6 26.0 -0.6 73.4 64.1 -12.7
 PHE-350   LEU-351  14.9 15.0 -4.8 -1.6 61.3 62.0 9.4
 PHE-350   LEU-351  14.9 15.0 -4.8 -1.6 61.3 62.0 9.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-350   LEU-351  14.9 15.0 -4.8 -1.6 61.3 62.0 9.4
 PHE-350   LEU-351  14.9 15.0 -4.8 -1.6 61.3 62.0 9.4
 LEU-351   SER-352  11.5 11.7 -6.2 4.4 9.5 9.9 30.3
 SER-352   GLU-353  11.8 12.0 -13.2 8.8 57.3 55.5 -2.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees