Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-714   GLY-715  8.5 7.8 -1.5 -12.1 72.3 75.4 33.6
 GLY-715   PRO-716  4.9 4.1 23.2 -17.7 94.6 105.8 4.8
 PRO-716   GLU-717  2.5 2.2 -86.5 73.5 37.5 34.6 77.2
 GLU-717   ILE-718  5.1 5.1 11.3 -11.7 94.7 97.1 -33.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-815   ASP-816  7.3 6.6 -13.2 8.4 16.6 21.6 -7.3
 ASP-816   LEU-817  8.1 7.6 -12.3 15.5 54.2 47.6 54.2
 LEU-817   PRO-818  5.1 4.9 10.4 -13.4 125.3 122.6 26.0
 PRO-818   ALA-819  3.5 3.0 -20.9 4.5 112.5 106.9 -25.0
 ALA-819   VAL-820  3.7 2.8 1.5 -0.3 99.9 120.0 4.0
 VAL-820   SER-821  2.2 2.1 -16.2 -24.7 76.3 68.3 120.8
 SER-821   GLU-822  3.0 2.5 3.3 2.2 158.7 144.6 -45.0
 GLU-822   LYS-823  4.8 4.9 -0.2 0.2 93.3 103.2 8.8
 LYS-823   ASP-824  7.6 7.5 -4.3 -9.8 91.1 92.2 -11.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees