Alcohol Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-169   CYS-170  6.9 6.8 4.0 -2.4 128.8 127.1 -17.1
 CYS-170   LEU-171  7.0 7.0 -3.6 -2.7 56.2 57.9 13.3
 LEU-171   ILE-172  3.4 3.4 5.1 -5.9 151.9 146.3 58.5
 ILE-172   GLY-173  4.7 4.5 -3.3 1.2 45.7 40.4 -17.0
 GLY-173   CYS-174  6.2 6.2 5.6 0.6 123.7 122.6 -45.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-175   PHE-176  2.5 2.5 12.6 -13.9 92.5 91.3 5.2
 PHE-176   SER-177  1.6 1.6 -0.8 3.2 27.8 28.0 -22.1
 SER-177   THR-178  2.6 2.8 -1.0 -1.0 44.3 45.2 38.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-289   VAL-290  14.2 14.1 10.2 -11.6 88.0 87.5 27.0
 VAL-290   ILE-291  10.7 10.6 -1.0 -3.6 67.1 64.7 88.6
 ILE-291   VAL-292  9.9 10.2 8.9 -10.3 122.4 120.3 35.8
 VAL-292   ALA-293  7.7 8.1 -23.7 90.9 76.9 73.4 -164.1
 ALA-293   VAL-294  9.7 10.7 -4.3 72.3 124.9 131.7 627.3
 VAL-294   THR-295  12.4 11.6 -15.2 -12.9 73.7 100.5 165.3
 THR-295   PRO-296  15.0 14.9 26.5 -11.0 42.6 88.9 41.7
 PRO-296   ASP-297  15.5 18.1 172.6 32.3 58.1 27.7 -1704.0
 ASP-297   SER-298  19.0 18.4 71.3 87.7 54.1 41.2 1405.1
 SER-298   GLN-299  17.6 19.2 -90.3 17.9 114.5 89.2 -263.1
 GLN-299   ASN-300  19.9 20.1 -20.4 -13.9 116.9 114.2 -230.2
 ASN-300   LEU-301  19.4 19.3 9.7 -10.9 112.0 111.2 -26.5
 LEU-301   SER-302  19.6 19.7 -1.1 -0.5 141.9 143.7 -19.9
 SER-302   MET-303  22.0 22.0 -0.1 1.2 84.5 80.0 -47.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-317   ILE-318  3.1 3.5 -4.5 -3.6 43.9 47.5 16.3
 ILE-318   PHE-319  2.5 2.7 -11.9 1.8 59.3 57.5 125.4
 PHE-319   GLY-320  1.5 1.4 -1.3 5.4 93.4 92.2 31.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-342   ASP-343  4.2 3.8 -2.2 5.5 135.9 138.1 30.9
 ASP-343   PRO-344  3.2 3.3 -4.6 -0.7 86.7 86.9 55.2
 PRO-344   LEU-345  5.6 5.6 0.3 6.4 121.9 118.8 -60.1
 LEU-345   ILE-346  4.0 4.0 -6.5 1.9 117.1 121.6 2.6
 ILE-346   THR-347  2.9 3.1 0.6 -1.4 42.6 40.3 -12.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees