Tissue Factor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-105   LEU-106  6.0 6.1 0.2 -2.6 86.2 87.2 16.8
 LEU-106   GLY-107  2.4 2.5 -2.0 5.3 158.9 158.9 21.9
 GLY-107   GLN-108  3.5 3.6 -2.7 3.2 122.4 119.0 5.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-126   ASP-127  12.4 12.6 0.6 5.8 36.2 31.8 35.2
 ASP-127   ALA-128  11.7 12.2 0.9 -10.0 96.5 99.0 3.9
 ALA-128   ARG-129  9.2 9.6 11.3 26.3 40.3 42.3 197.9
 ARG-129   THR-130  11.0 10.9 -38.3 38.0 72.8 90.2 71.8
 THR-130   LEU-131  12.1 9.8 46.8 -13.4 73.5 82.9 35.2
 LEU-131   VAL-132  15.8 12.4 -109.5 21.8 123.6 166.5 -653.9
 THR-137   PHE-138  19.0 18.4 -37.1 34.4 53.1 79.8 57.0
 PHE-138   LEU-139  15.8 15.2 -42.9 45.7 128.8 106.5 6.7
 LEU-139   SER-140  12.2 12.6 35.7 2.5 120.5 131.4 -234.1
 SER-140   LEU-141  10.4 10.5 19.3 6.1 79.5 78.7 81.4
 LEU-141   ARG-142  6.7 6.8 -2.3 9.7 129.9 130.8 30.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-194   LYS-195  8.3 8.6 13.8 -12.5 111.9 109.9 23.8
 LYS-195   ARG-196  11.9 12.2 3.4 0.4 158.3 157.4 -33.9
 ARG-196   LYS-197  11.2 11.4 -2.5 -1.6 80.4 80.0 15.4
 LYS-197   GLN-198  8.1 8.4 -2.4 -0.8 74.5 74.1 5.6
 LYS-197   GLN-198  8.1 8.4 -2.4 -0.8 74.5 74.1 5.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-197   GLN-198  8.1 8.4 -2.4 -0.8 74.5 74.1 5.6
 LYS-197   GLN-198  8.1 8.4 -2.4 -0.8 74.5 74.1 5.6
 GLN-198   ARG-199  7.1 7.2 6.8 1.3 53.2 52.8 26.6
 ARG-199   SER-200  5.3 5.5 -2.1 4.3 121.3 119.0 22.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees