Pyruvate Kinase Isozymes M1/m2
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-113
LYS-114
5.9
5.8
-5.3
7.0
45.7
50.2
1.7
LYS-114
GLY-115
6.3
6.2
-7.9
-4.3
70.6
64.5
24.1
GLY-115
PRO-116
3.3
3.3
10.8
3.3
98.0
106.1
-24.2
PRO-116
GLU-117
5.7
5.6
-63.4
43.6
24.5
39.2
86.5
GLU-117
ILE-118
8.0
7.5
-29.4
11.7
87.5
85.0
46.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-217
PRO-218
9.6
9.7
-6.7
5.5
50.5
62.5
-11.5
PRO-218
ALA-219
7.8
7.7
0.5
-15.4
72.2
68.9
-11.2
ALA-219
VAL-220
5.1
4.9
10.5
-7.6
107.4
126.4
31.5
VAL-220
SER-221
2.7
3.0
-19.2
-8.1
70.0
57.8
69.7
SER-221
GLU-222
5.3
5.4
4.3
-2.7
157.8
153.3
-12.4
GLU-222
LYS-223
6.9
6.3
-1.8
5.4
86.4
95.9
-11.4
LYS-223
ASP-224
7.3
6.9
-4.2
-3.5
90.1
100.9
-0.9
ASP-224
ILE-225
3.9
3.6
4.8
-8.7
154.3
145.4
33.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees