Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-85   GLY-86  8.2 8.4 -10.9 4.5 104.9 93.0 -3.9
 GLY-86   PRO-87  7.2 7.2 6.1 -0.6 143.3 149.6 -3.0
 PRO-87   GLU-88  6.7 5.8 -20.4 51.8 64.0 63.9 -11.6
 GLU-88   ILE-89  3.7 3.3 6.5 -21.6 178.2 162.2 23.2
 ILE-89   ARG-90  2.4 2.0 4.3 -7.2 100.1 106.2 5.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-125   ILE-126  3.9 1.8 -1.0 3.9 26.5 8.1 -6.0
 ILE-126   ASP-127  2.1 1.4 22.3 -8.8 100.4 101.5 3.8
 ASP-127   TYR-128  5.2 4.8 5.9 -32.5 108.4 114.3 19.5
 TYR-128   GLN-129  5.7 5.5 -19.2 -1.9 140.6 133.1 -17.6
 GLN-129   ASN-130  8.8 8.0 11.6 36.1 65.6 98.1 6.6
 ASN-130   LEU-131  9.9 9.7 -45.1 8.8 83.6 89.4 -7.7
 LEU-131   SER-132  7.3 7.4 -7.7 11.0 130.4 125.2 -0.9
 SER-132   LYS-133  9.0 9.7 -2.6 -8.9 77.1 65.2 -5.3
 LYS-133   VAL-134  12.3 12.6 6.7 -34.8 136.4 143.4 28.0
 VAL-134   VAL-135  11.4 12.1 31.9 2.4 80.8 88.8 -4.2
 VAL-135   ARG-136  11.4 11.7 -39.4 24.0 147.8 131.0 -22.6
 ARG-136   PRO-137  14.0 15.3 -2.0 12.0 107.3 114.8 9.2
 PRO-137   GLY-138  14.4 16.8 -15.1 -19.5 49.4 47.5 25.4
 GLY-138   ASN-139  16.0 17.0 55.6 -24.5 154.4 145.7 -35.0
 ASN-139   TYR-140  13.7 14.0 2.7 -14.6 94.3 88.3 -5.7
 TYR-140   ILE-141  11.6 12.0 -10.1 -10.3 76.1 81.2 11.2
 ILE-141   TYR-142  8.0 8.5 -6.7 3.1 60.8 80.6 13.7
 TYR-142   ILE-143  8.0 8.6 21.6 -21.3 90.1 75.3 -0.4
 ILE-143   ASP-144  7.3 7.7 -8.8 1.9 46.9 67.9 2.0
 ASP-144   ASP-145  8.6 9.4 27.8 -0.6 144.9 138.8 -12.8
 ASP-145   GLY-146  8.3 10.3 -7.1 -6.2 105.3 95.6 -0.5
 GLY-146   ILE-147  10.1 10.9 12.5 -19.1 75.8 59.1 3.2
 ILE-147   LEU-148  13.0 13.6 13.1 -2.2 17.7 29.1 12.7
 LEU-148   ILE-149  12.1 12.3 16.1 -17.2 84.2 102.0 3.3
 ILE-149   LEU-150  11.9 12.5 -4.3 -13.4 173.8 150.7 -19.5
 LEU-150   GLN-151  10.8 11.5 -13.7 -3.9 95.3 82.6 8.2
 GLN-151   VAL-152  12.6 13.8 1.1 -3.3 36.4 38.3 -7.2
 GLN-153   SER-154  13.0 10.7 171.3 54.3 61.1 139.1 -29.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees