Phenylalanine-4-Hydroxylase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-193   LEU-194  8.3 8.6 -1.8 -0.7 52.8 53.3 -23.1  LEU-194   LYS-195  6.1 6.4 2.4 -0.4 61.0 59.7 40.1  LYS-195   SER-196  4.1 4.1 3.9 10.6 65.3 63.8 21.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  PHE-219   HIS-220  6.6 7.0 -1.2 -2.7 34.2 28.1 25.0  HIS-220   GLU-221  5.7 6.4 2.0 10.0 81.9 84.0 8.6  GLU-221   ASP-222  6.4 7.0 -1.1 -10.3 73.4 88.0 3.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ASP-315   GLU-316  2.7 2.0 -7.2 3.5 96.6 102.3 -11.3  GLU-316   TYR-317  2.0 2.4 -14.7 6.5 128.5 136.9 -34.7  TYR-317   ILE-318  2.4 3.1 4.4 4.4 24.0 29.2 46.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ALA-389   GLU-390  15.9 15.2 -11.4 -5.4 56.7 57.4 24.3  GLU-390   SER-391  19.1 18.4 -7.8 -4.0 36.4 52.0 53.8  SER-391   PHE-392  17.2 16.7 -1.2 -9.7 103.0 121.4 -27.8 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees