3-Isopropylmalate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-107   LEU-108  1.8 1.8 -8.9 14.6 125.0 125.9 -2.7
 LEU-108   ARG-109  3.0 3.4 17.5 -10.5 20.5 22.0 36.5
 ARG-109   PRO-110  3.8 4.1 0.8 2.4 57.3 57.5 0.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-267   PRO-268  1.8 1.8 20.4 2.1 49.0 50.0 60.3
 PRO-268   SER-269  0.9 0.9 2.9 -8.3 24.1 25.1 -30.6
 SER-269   ALA-270  1.3 0.9 7.9 0.4 52.6 52.9 17.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-335   THR-336  0.8 1.2 24.3 -7.2 90.7 86.3 3.5
 THR-336   GLY-337  3.9 4.7 167.4 -155.7 74.2 63.2 53.6
 GLY-337   ASP-338  6.3 5.3 88.8 -66.1 119.0 124.3 -33.0
 ASP-338   LEU-339  6.7 4.7 15.4 -48.1 78.3 53.6 -54.1
 LEU-339   ALA-340  4.6 4.4 70.7 12.9 15.7 40.8 317.0
 ALA-340   ARG-341  4.6 4.3 64.9 -119.7 75.2 30.9 -54.4
 ARG-341   GLY-342  8.1 4.9 -82.2 117.6 134.6 141.9 31.0
 GLY-342   ALA-343  7.9 1.9 107.1 162.3 39.8 121.3 -2.1
 ALA-343   ALA-344  6.0 3.5 10.4 -145.9 96.5 155.8 -468.3
 ALA-344   ALA-345  2.9 3.5 78.7 20.3 148.9 85.7 393.4
 ALA-345   VAL-346  4.0 3.8 -140.3 -74.4 92.4 55.3 -184.4
 VAL-346   SER-347  6.2 6.5 -27.3 11.1 47.6 57.5 32.3
 SER-347   THR-348  9.2 9.3 8.7 -16.2 153.7 155.4 3.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees