Immunoglobulin Gamma-1 Heavy Chain Constant Region

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  SER-337   LYS-338  6.5 6.7 4.4 -24.5 115.7 119.8 63.7  LYS-338   ALA-339  3.7 4.0 -13.6 40.0 126.9 111.9 27.9  ALA-339   LYS-340  0.5 0.3 -29.4 18.8 78.8 93.8 10.0  LYS-340   GLY-341  3.3 3.4 22.5 -45.7 101.3 110.5 33.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees