Epidermal Growth Factor Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  CYS-302   LYS-303  4.6 4.9 4.9 -20.9 62.5 70.8 -43.7  LYS-303   LYS-304  1.6 2.0 8.7 -4.5 148.6 145.3 -33.3  LYS-304   CYS-305  1.8 2.4 -7.3 -15.3 75.4 76.0 220.0  CYS-305   GLU-306  4.5 5.2 -2.3 -8.9 101.6 87.7 57.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees