Receptor Tyrosine-Protein Kinase Erbb-4

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-236   CYS-237  18.4 18.3 -1.7 10.2 52.1 59.6 -41.6
 CYS-237   PRO-238  16.3 16.1 -26.7 -3.9 49.1 56.3 82.4
 PRO-238   GLN-239  13.9 13.8 0.8 -21.3 61.7 62.9 -46.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-253   PHE-254  6.5 6.3 -1.1 26.5 80.8 103.0 3.2
 PHE-254   ASN-255  8.5 7.9 -66.9 58.7 87.4 73.2 25.0
 ASN-255   ALA-256  11.6 11.4 -17.5 -1.3 33.8 17.0 52.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-286   LYS-287  2.2 3.1 -42.5 -9.9 36.9 24.7 214.8
 LYS-287   MET-288  1.9 5.2 17.1 -20.4 75.0 89.1 -22.8
 MET-288   GLU-289  5.6 8.8 24.1 -26.7 135.4 149.2 3.4
 GLU-289   VAL-290  8.1 11.3 7.7 -25.2 130.8 125.5 89.1
 VAL-290   GLU-291  9.1 12.3 99.5 -74.7 133.8 148.5 -122.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-298   LYS-299  4.5 7.2 14.6 -8.0 113.7 110.1 -32.5
 LYS-299   PRO-300  3.1 5.3 19.2 -20.1 38.8 23.8 -16.9
 PRO-300   CYS-301  3.1 3.8 -10.7 37.2 104.2 106.2 80.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees