Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-207   ASP-208  1.4 1.0 10.4 -8.9 104.7 107.2 10.8
 ASP-208   THR-209  2.6 3.0 18.5 4.6 74.7 73.7 1.1
 THR-209   LEU-210  4.8 5.1 -16.4 0.7 34.4 30.5 44.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-342   GLN-343  2.5 2.8 -1.0 1.2 158.6 154.3 -3.3
 GLN-343   SER-344  1.4 1.5 -31.2 -11.4 90.2 89.6 0.7
 SER-344   PRO-345  4.9 5.2 28.4 -6.7 26.3 22.7 70.2
 PRO-345   GLU-346  5.8 6.3 17.2 20.8 79.0 90.1 -9.4
 GLU-346   VAL-347  8.7 9.6 8.9 6.1 84.4 82.9 17.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-473   ASP-474  11.1 10.6 10.3 -12.5 130.8 132.4 1.0
 ASP-474   ALA-475  8.2 7.9 5.3 -10.5 156.8 151.7 30.2
 ALA-475   PRO-476  8.2 8.1 -13.6 -2.0 65.2 65.5 24.5
 PRO-476   GLY-477  7.9 7.2 -4.2 -45.3 66.7 45.8 67.1
 GLY-477   ARG-478  4.8 4.4 49.3 -27.4 155.2 109.3 -53.5
 ARG-478   TYR-479  4.0 3.2 54.1 -3.4 99.9 105.2 -41.0
 TYR-479   ASP-480  3.3 3.3 -10.8 -4.8 31.3 26.3 50.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees