Alcohol Dehydrogenase (Holo Form) (E.C.1.1.1.1)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-175   PHE-176  4.4 4.5 -7.2 -7.8 91.3 93.3 -2.9
 PHE-176   SER-177  1.2 1.3 8.8 -5.9 29.5 31.4 20.6
 SER-177   THR-178  3.1 3.0 -5.1 7.5 141.1 138.7 -5.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 SER-289   VAL-290  11.0 10.9 -3.0 -3.5 90.2 94.1 -31.9
 VAL-290   ILE-291  7.7 7.6 3.8 -4.6 65.1 62.6 44.0
 ILE-291   VAL-292  8.3 8.0 -12.0 28.9 122.6 122.5 210.9
 VAL-292   GLY-293  6.9 6.2 1.7 -96.4 74.4 88.1 -172.1
 GLY-293   VAL-294  10.3 8.8 17.0 -65.4 128.7 115.6 462.0
 VAL-294   PRO-295  12.1 12.1 9.8 16.3 103.7 73.9 121.6
 PRO-295   PRO-296  15.1 15.1 -13.2 -5.6 93.6 38.6 64.8
 PRO-296   ASP-297  18.7 16.2 -140.5 -71.0 31.2 62.5 -1430.5
 ASP-297   SER-298  19.4 19.3 -109.2 -131.6 38.3 66.4 1926.7
 SER-298   GLN-299  19.9 17.8 128.4 1.8 97.9 160.1 -867.1
 GLN-299   ASN-300  20.3 19.5 30.1 39.8 117.4 114.7 -277.2
 ASN-300   LEU-301  19.0 18.5 1.6 -9.7 72.7 67.3 -60.4
 LEU-301   SER-302  18.6 18.4 -9.3 17.5 29.7 34.3 -69.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 TRP-314   LYS-315  9.1 8.9 -10.6 15.3 93.9 94.6 -2.5
 LYS-315   GLY-316  5.7 5.5 -5.7 -2.5 142.1 136.6 46.2
 GLY-316   ALA-317  4.8 4.2 -13.2 -0.6 102.0 103.8 -48.8
 ALA-317   ILE-318  2.8 2.5 5.3 -16.0 43.0 48.3 -92.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLU-366   SER-367  15.6 14.7 127.4 -39.9 87.1 126.4 -284.3
 SER-367   ILE-368  12.2 12.1 -63.2 37.8 145.2 137.3 -308.5
 ILE-368   ARG-369  9.4 9.1 25.5 -35.6 81.6 71.5 -59.7
 ARG-369   THR-370  8.0 8.0 -1.3 -3.8 30.1 36.3 75.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees