Proto-Oncogene Tyrosine-Protein Kinase Fes/fps

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-559   ASP-560  17.3 16.9 6.3 4.9 48.8 51.6 130.3
 ASP-560   LEU-561  14.1 14.0 4.4 7.6 85.9 84.9 38.2
 LEU-561   VAL-562  12.2 12.0 2.4 11.2 80.7 67.3 39.8
 VAL-562   LEU-563  13.3 12.9 -20.5 11.3 65.4 61.8 42.2
 LEU-563   GLY-564  12.9 13.1 -8.9 8.0 121.9 125.7 -38.5
 GLY-564   GLU-565  13.3 13.4 9.0 -0.5 134.7 135.5 -49.5
 GLU-565   GLN-566  14.7 14.9 -11.8 3.2 39.5 26.6 127.7
 GLN-566   ILE-567  14.0 14.7 -1.0 -3.4 106.4 91.8 -18.8
 ILE-567   GLY-568  12.4 13.2 38.2 -73.4 145.7 155.0 393.5
 GLY-568   ARG-569  12.1 14.0 27.4 -6.2 142.0 132.2 -374.7
 ARG-569   GLY-570  12.3 12.5 18.8 1.1 126.2 112.7 -40.2
 GLY-570   ASN-571  9.4 9.3 9.7 -0.5 154.8 163.9 -100.8
 ASN-571   PHE-572  8.8 8.5 4.7 -25.6 95.0 102.5 46.1
 PHE-572   GLY-573  8.4 8.9 12.5 24.0 59.4 53.3 265.3
 GLY-573   GLU-574  11.2 11.4 -14.6 2.4 157.5 150.5 -187.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-575   PHE-576  9.3 10.2 3.8 -3.0 151.4 152.5 14.9
 PHE-576   SER-577  10.4 11.0 -5.8 1.7 42.7 46.4 55.6
 SER-577   GLY-578  9.0 9.5 -11.6 0.2 76.8 68.4 31.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-584   THR-585  7.1 6.9 1.2 -7.5 118.4 114.6 51.8
 THR-585   LEU-586  4.4 3.9 12.8 -3.5 128.0 134.1 -122.8
 LEU-586   VAL-587  4.4 3.9 -9.8 7.1 25.4 18.4 58.2
 VAL-587   ALA-588  4.1 4.1 -2.4 4.8 49.8 51.6 -27.5
 ALA-588   VAL-589  4.9 5.3 -8.9 12.9 49.3 53.9 -6.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-591   CYS-592  9.6 10.1 -14.9 29.7 168.7 172.2 97.3
 CYS-592   ARG-593  10.4 10.6 -3.8 18.2 108.9 103.7 69.9
 ARG-593   GLU-594  13.5 13.7 -13.6 2.6 135.8 120.0 -121.4
 GLU-594   THR-595  15.4 16.0 8.1 -21.4 19.8 14.8 -165.7
 THR-595   LEU-596  16.0 16.8 29.1 -10.6 58.9 55.5 157.4
 LEU-596   PRO-597  12.4 13.2 9.8 -0.2 41.2 49.3 47.2
 PRO-597   PRO-598  11.3 12.5 -6.1 -5.5 73.2 62.4 -30.1
 PRO-598   ASP-599  11.1 12.7 23.4 -2.9 90.0 73.9 -79.2
 ASP-599   LEU-600  7.6 9.5 6.7 -18.7 139.0 128.3 64.2
 LEU-600   LYS-601  6.3 7.7 27.9 -6.3 147.1 162.9 -215.4
 LYS-601   ALA-602  8.6 9.2 15.0 -11.3 95.1 91.6 -64.6
 ALA-602   LYS-603  8.1 7.5 -35.6 32.1 65.5 75.0 61.1
 LYS-603   PHE-604  4.6 3.7 -17.3 -17.6 11.7 14.0 398.1
 PHE-604   LEU-605  5.4 4.8 -10.9 7.9 47.6 55.8 18.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-609   ILE-610  8.5 8.5 -1.2 8.5 102.2 99.1 -2.2
 ILE-610   LEU-611  8.0 8.1 2.0 3.3 12.8 12.6 97.6
 LEU-611   LYS-612  7.3 7.1 -3.0 -2.2 123.3 125.0 -75.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-617   ASN-618  12.4 12.3 -2.4 1.3 118.3 115.7 -37.1
 ASN-618   ILE-619  12.3 12.2 2.8 1.8 38.1 38.4 26.7
 ILE-619   VAL-620  9.4 9.3 0.0 -2.4 60.3 59.7 13.7
 VAL-620   ARG-621  5.7 5.7 2.7 -5.3 90.0 88.3 -26.1
 ARG-621   LEU-622  5.3 4.9 1.9 -1.6 72.0 75.9 17.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-633   ILE-634  9.5 9.6 -4.0 1.7 96.1 89.8 20.7
 ILE-634   VAL-635  6.1 6.2 3.8 0.6 28.7 27.5 17.8
 VAL-635   MET-636  5.2 5.2 -5.2 9.3 103.5 102.5 49.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees