Insulin Receptor Tyrosine Kinase Domain
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-1010
TYR-1011
11.2
11.5
-0.5
0.8
147.7
147.5
-11.2
TYR-1011
GLU-1012
10.7
10.9
0.9
-0.7
84.2
84.0
20.8
GLU-1012
GLY-1013
10.0
10.3
-3.3
1.5
145.3
146.1
4.7
GLY-1013
ASN-1014
7.4
7.6
3.7
-10.4
77.6
79.6
3.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-1050
MET-1051
5.3
5.3
14.0
-9.4
76.6
74.4
12.5
MET-1051
LYS-1052
1.9
2.6
8.3
1.4
61.8
64.5
86.3
LYS-1052
GLY-1053
4.7
5.9
1.0
-0.3
130.6
129.8
-29.0
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLN-1070
PRO-1071
14.4
14.5
11.6
9.4
121.8
134.1
10.6
PRO-1071
THR-1072
12.8
13.0
-9.7
6.4
110.6
113.7
37.0
THR-1072
LEU-1073
10.6
10.8
-5.0
-0.4
98.1
90.5
-11.7
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-1074
VAL-1075
4.5
4.5
0.0
0.2
110.2
107.7
-10.7
VAL-1075
MET-1076
1.7
1.8
-3.4
3.9
44.7
47.9
-4.2
MET-1076
GLU-1077
3.3
3.6
9.5
-4.0
64.2
63.6
51.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees