Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LYS-536   MET-537  11.6 11.9 -12.7 19.5 161.1 155.8 53.1
 MET-537   ILE-538  10.8 10.9 -28.3 25.6 97.5 90.7 -48.5
 ILE-538   GLY-539  7.0 7.2 -1.4 -5.6 78.2 75.8 1.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ILE-544   ILE-545  1.1 1.1 31.3 -21.9 39.1 42.5 52.5
 ILE-545   ASN-546  2.9 3.2 -6.2 -10.4 70.2 60.4 58.6
 ASN-546   LEU-547  5.5 5.6 8.2 2.2 62.9 61.8 56.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLU-562   TYR-563  5.5 5.3 5.3 -5.3 127.9 134.3 2.2
 TYR-563   ALA-564  3.8 3.7 10.3 -11.5 86.6 88.9 -15.7
 ALA-564   SER-565  1.7 1.7 -1.4 -7.7 28.2 23.0 50.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LYS-638   ILE-639  3.3 3.2 2.8 3.1 106.6 105.0 -16.6
 ILE-639   ALA-640  5.4 5.3 13.7 3.5 75.8 76.9 40.4
 ALA-640   ASP-641  7.2 7.2 -22.0 -6.1 72.9 59.2 91.2
 ASP-641   PHE-642  10.8 10.3 -29.6 1.3 14.7 10.9 208.0
 PHE-642   GLY-643  11.2 9.0 -31.6 -44.8 78.8 57.0 101.9
 GLY-643   LEU-644  15.0 11.0 65.9 -13.9 138.2 79.4 -121.6
 LEU-644   ALA-645  16.0 14.4 -176.5 -100.5 32.9 39.9 -622.5
 ALA-645   ARG-646  13.0 17.4 17.0 -29.0 135.7 65.2 61.6
 ASN-659   GLY-660  28.2 23.9 -150.0 150.1 153.1 169.3 -4.0
 GLY-660   ARG-661  27.0 22.1 156.4 -83.5 68.6 66.4 243.2
 ARG-661   LEU-662  25.0 21.1 -112.6 -144.9 59.3 54.9 -637.6
 LEU-662   PRO-663  23.0 23.5 -82.8 20.5 115.3 40.7 -40.5
 PRO-663   VAL-664  21.4 21.1 -106.2 8.5 53.4 41.6 457.1
 VAL-664   LYS-665  24.0 23.7 6.6 -4.5 89.0 97.3 -1.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees