Glutamate Receptor Ionotropic, Nmda 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  PHE-141   LYS-142  5.3 5.2 1.8 -10.6 148.3 146.1 83.6  LYS-142   TYR-143  5.7 5.3 3.2 22.6 132.9 133.0 -194.5  TYR-143   GLN-144  6.2 6.5 9.5 30.9 132.9 111.6 -302.3  GLN-144   GLY-145  8.3 9.5 -38.6 -6.7 50.3 18.3 436.0  GLY-145   LEU-146  10.7 10.7 -16.3 -17.8 61.9 64.6 90.6  LEU-146   THR-147  12.9 12.4 9.6 -0.1 134.1 136.2 -87.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLU-243   LEU-244  6.4 5.8 10.3 -1.3 133.5 130.9 -91.9  LEU-244   PHE-245  8.2 7.6 -10.9 7.2 99.3 98.5 -39.6  PHE-245   PHE-246  11.3 10.7 -5.6 5.2 36.2 42.1 42.9  PHE-246   ARG-247  13.8 13.6 0.3 -10.8 141.9 151.8 70.0  ARG-247   SER-248  11.0 11.2 9.1 -17.1 150.1 144.8 96.2  SER-248   GLY-249  11.8 11.7 25.4 -14.0 130.7 130.3 -116.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-282   THR-283  11.4 11.1 -6.8 4.3 114.8 112.7 -8.2  THR-283   TRP-284  13.3 13.3 -11.9 19.4 69.5 74.2 45.9  TRP-284   VAL-285  13.2 13.4 8.1 -5.9 162.1 158.3 17.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees