Transportin-1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-144   CYS-145  18.8 23.4 -88.0 115.1 59.4 161.4 68.8
 CYS-145   GLU-146  18.3 21.8 106.5 -8.8 115.2 59.2 -45.6
 GLU-146   GLY-147  16.4 19.8 -129.1 178.9 124.6 97.0 207.1
 GLY-147   ALA-148  12.9 23.0 20.8 128.1 63.3 41.6 -603.8
 ALA-148   PHE-149  14.1 25.1 -6.8 75.7 145.5 156.8 269.2
 PHE-149   GLY-150  14.8 22.6 -22.5 8.5 81.1 110.3 -7.8
 PHE-149   GLY-150  14.8 22.6 -22.5 8.5 81.1 110.3 -7.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-149   GLY-150  14.8 22.6 -22.5 8.5 81.1 110.3 -7.8
 PHE-149   GLY-150  14.8 22.6 -22.5 8.5 81.1 110.3 -7.8
 GLY-150   ALA-151  14.8 22.4 -79.2 96.0 68.8 113.8 -26.8
 ALA-151   LEU-152  18.4 26.2 -6.7 36.2 132.7 145.9 62.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-159   ALA-160  23.9 31.2 138.8 -3.8 157.1 163.8 -493.9
 ALA-160   GLU-161  22.0 31.3 3.8 1.8 103.4 112.5 -53.8
 GLU-161   ILE-162  24.6 33.0 -168.5 -10.6 83.1 124.8 371.8
 ILE-162   LEU-163  27.6 30.7 -101.9 -78.2 33.4 143.6 104.0
 LEU-163   ASP-164  26.9 31.8 -162.5 -67.5 31.4 76.3 -492.8
 ASP-164   SER-165  25.4 33.6 -145.6 38.7 84.8 138.3 601.9
 SER-165   ASP-166  28.0 35.5 -69.0 123.9 99.2 118.8 -315.2
 ARG-170   PRO-171  36.4 34.3 84.7 -10.9 35.7 173.4 479.6
 PRO-171   LEU-172  38.0 33.8 -161.2 85.1 144.7 84.8 -205.6
 LEU-172   ASN-173  35.4 30.4 -46.5 13.5 70.5 82.5 78.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-183   LYS-184  18.7 15.0 10.9 -38.1 74.1 123.8 -25.1
 LYS-184   HIS-185  16.6 14.5 31.6 -2.8 142.9 164.4 -102.6
 HIS-185   SER-186  16.8 14.4 -133.9 -18.3 65.2 75.7 222.3
 SER-186   SER-187  15.0 11.3 -141.2 102.7 127.6 93.0 -41.1
 SER-187   PRO-188  11.7 11.3 170.8 19.2 114.9 23.9 332.0
 PRO-188   LYS-189  9.9 10.3 -38.5 -7.2 16.7 100.9 51.9
 LYS-189   ILE-190  10.1 13.6 174.3 -0.4 97.4 64.7 190.3
 ILE-190   ARG-191  6.7 15.6 -21.8 8.4 87.3 160.4 -47.0
 ARG-191   SER-192  8.4 13.9 170.1 8.4 31.2 48.4 -532.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees