Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-207   ASP-208  11.6 11.9 21.8 -8.7 35.7 31.9 173.1
 ASP-208   THR-209  11.4 11.6 7.1 4.0 96.8 103.3 -59.6
 THR-209   LEU-210  10.6 10.6 -8.7 -7.3 97.4 104.9 -67.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-231   THR-232  16.2 16.8 -5.4 -18.1 77.4 76.2 73.6
 THR-232   GLU-233  18.4 19.0 8.0 2.8 52.4 45.3 145.1
 GLU-233   GLY-234  22.0 22.5 -6.2 2.0 131.2 127.6 -44.6
 GLY-234   ASN-235  23.2 23.0 -54.3 36.9 151.5 144.9 -210.9
 ASN-235   TYR-236  21.6 21.8 43.7 -33.8 93.6 94.0 33.1
 TYR-236   GLY-237  18.2 18.5 -29.3 10.8 67.3 69.5 79.3
 GLY-237   GLU-238  17.8 17.5 7.5 2.7 51.1 59.7 -13.8
 GLU-238   SER-239  19.6 19.6 -11.2 -5.8 143.8 145.2 -191.7
 SER-239   GLY-240  17.7 18.1 30.2 -13.8 99.5 97.0 47.0
 GLY-240   MET-241  14.2 14.5 3.3 1.5 108.0 109.0 47.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-340   LYS-341  5.9 5.6 6.3 -32.4 88.2 83.5 -115.6
 LYS-341   LEU-342  9.0 8.8 -29.0 36.5 171.2 152.2 121.1
 LEU-342   GLN-343  10.8 10.7 -8.9 -0.9 105.6 93.6 -1.9
 GLN-343   SER-344  11.3 11.4 -7.4 41.3 114.3 118.0 214.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-480   ILE-481  6.8 7.2 12.6 -9.6 41.2 47.2 -0.3
 ILE-481   MET-482  4.2 4.6 -12.9 21.5 148.5 155.1 107.5
 MET-482   ASN-483  5.5 5.8 -3.1 1.8 140.2 135.0 43.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-499   TRP-500  5.9 6.2 13.7 -19.0 57.4 56.2 -43.1
 TRP-500   HIS-501  3.1 3.6 -12.8 14.8 151.8 154.1 55.1
 HIS-501   GLU-502  4.4 5.0 -27.2 31.0 135.1 137.8 52.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-505   ASN-506  4.6 4.9 2.4 -0.8 71.8 64.3 50.3
 ASN-506   ILE-507  7.1 7.5 31.6 -31.4 13.1 16.7 29.8
 ILE-507   ASP-508  7.5 8.1 17.3 -19.5 68.5 66.9 45.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees