Nicotinamide Phosphoribosyltransferase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-173   LYS-174  7.4 7.4 -3.8 7.7 41.1 39.3 -37.8
 LYS-174   TYR-175  6.4 6.9 -1.6 -6.2 103.7 99.4 -32.1
 TYR-175   LEU-176  4.6 5.2 0.1 6.6 62.2 62.2 38.7
 LEU-176   LEU-177  2.4 2.6 -0.5 2.2 46.3 45.1 -2.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-241   VAL-242  10.3 10.5 -35.2 34.4 119.6 126.3 37.7
 VAL-242   PRO-243  7.1 7.3 4.3 -7.4 42.6 40.4 -24.1
 PRO-243   ALA-244  5.6 5.9 8.7 -11.2 110.4 106.3 -1.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-309   ILE-310  2.5 2.6 -17.4 34.3 70.6 72.6 -39.0
 ILE-310   ARG-311  6.3 6.3 14.3 -39.6 65.3 68.1 -168.3
 ARG-311   PRO-312  8.5 8.2 -15.6 -13.0 89.2 78.0 -90.5
 PRO-312   ASP-313  11.9 12.0 3.4 -85.6 115.9 94.2 285.6
 ASP-313   SER-314  15.4 14.2 -166.4 -61.3 122.2 93.9 654.0
 SER-314   GLY-315  17.9 17.7 -6.2 -29.5 134.1 138.2 -255.5
 GLY-315   ASN-316  20.3 19.6 -36.2 4.4 151.6 153.2 -293.1
 ASN-316   PRO-317  19.6 19.7 -10.3 10.3 89.2 100.2 -9.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-327   LEU-328  16.1 16.1 2.9 3.2 78.6 81.0 5.1
 LEU-328   GLY-329  13.2 13.1 7.3 -13.3 131.3 128.0 65.1
 GLY-329   LYS-330  14.1 14.1 -18.0 17.5 95.8 102.9 33.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-333   VAL-334  15.4 15.4 -13.9 7.2 130.1 132.2 -48.7
 VAL-334   SER-335  13.4 13.4 2.0 2.2 38.0 34.6 37.4
 SER-335   GLU-336  13.1 13.0 -2.1 -0.9 145.6 141.1 -45.1
 GLU-336   ASN-337  11.9 11.8 -16.4 11.6 112.3 119.1 -1.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-340   TYR-341  9.9 9.7 -20.2 15.3 50.6 42.4 19.6
 TYR-341   LYS-342  8.5 8.5 -4.7 -6.0 23.9 29.5 105.8
 LYS-342   LEU-343  10.0 10.2 3.0 -4.4 127.0 130.2 32.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-345   PRO-346  10.1 10.2 -7.0 6.9 106.9 110.2 37.4
 PRO-346   TYR-347  8.4 8.3 -0.1 0.8 157.3 157.9 9.3
 TYR-347   LEU-348  7.8 7.8 -13.4 12.5 99.6 100.3 -26.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-350   ILE-351  5.1 5.3 -12.1 11.6 100.9 99.2 0.8
 ILE-351   GLN-352  6.4 6.2 -20.3 26.1 88.5 86.2 57.4
 GLN-352   GLY-353  10.1 9.8 -8.7 2.1 83.1 75.4 -31.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-363   ILE-364  14.9 15.4 -1.0 0.8 120.9 114.6 -40.7
 ILE-364   VAL-365  12.5 13.1 -16.6 22.1 62.3 57.0 -110.7
 VAL-365   GLU-366  9.2 9.8 -14.2 -0.1 35.1 32.4 153.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-369   GLN-370  8.7 9.6 -8.8 6.3 112.1 113.9 8.7
 GLN-370   LYS-371  12.3 13.0 4.1 -6.7 122.0 122.6 29.9
 LYS-371   LYS-372  13.0 13.7 14.9 -8.4 92.0 96.0 -45.6
 LYS-372   TRP-373  10.5 11.2 16.4 -21.6 144.5 145.8 8.0
 TRP-373   SER-374  8.5 8.8 6.6 -8.9 77.3 79.9 -6.3
 SER-374   ILE-375  4.8 5.2 -11.3 7.4 55.3 53.4 12.4
 ILE-375   GLU-376  3.0 3.7 11.6 -12.8 136.5 132.2 4.3
 GLU-376   ASN-377  1.2 1.5 -9.4 16.7 24.0 24.3 -64.6
 ASN-377   VAL-378  3.4 4.0 -23.2 29.7 56.3 56.0 -38.1
 VAL-378   SER-379  4.0 4.5 12.0 -19.0 85.8 88.8 38.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees