Lysine-Specific Histone Demethylase 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LYS-421   HIS-422  6.2 5.8 0.0 2.5 141.2 141.8 -21.0
 HIS-422   VAL-423  5.0 4.6 -0.1 -4.6 95.0 96.1 -8.7
 VAL-423   LYS-424  1.5 1.4 -4.8 11.0 123.4 125.7 58.5
 LYS-424   ASP-425  2.6 1.8 10.5 -13.3 62.1 63.9 -4.3
 LYS-424   ASP-425  2.6 1.8 10.5 -13.3 62.1 63.9 -4.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LYS-424   ASP-425  2.6 1.8 10.5 -13.3 62.1 63.9 -4.3
 LYS-424   ASP-425  2.6 1.8 10.5 -13.3 62.1 63.9 -4.3
 ASP-425   GLU-426  6.2 4.8 -18.5 14.9 130.1 128.4 -1.0
 GLU-426   GLN-427  4.3 3.8 15.0 -11.0 118.0 120.5 10.6
 GLN-427   ILE-428  5.1 4.7 -4.7 8.5 76.2 73.8 5.0
 ILE-428   GLU-429  7.9 7.2 -2.4 -1.8 142.1 135.9 -16.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 PRO-516   SER-517  5.7 6.2 -13.8 12.2 51.9 44.9 17.7
 SER-517   ASP-518  5.2 5.9 0.7 -5.4 165.2 157.4 47.1
 ASP-518   VAL-519  5.8 6.1 8.6 -8.2 114.0 113.9 5.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees