Bifunctional P-450/nadph-P450 Reductase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-165   TYR-166  16.2 15.9 13.9 -7.4 82.2 88.6 -0.5
 TYR-166   ARG-167  16.6 16.5 2.4 -9.7 31.5 35.0 21.1
 ARG-167   ASP-168  14.7 14.5 13.3 5.4 38.9 25.9 -27.5
 ASP-168   GLN-169  15.5 14.0 -36.8 18.9 119.1 94.4 -69.7
 GLN-169   PRO-170  11.8 10.6 -36.5 -4.6 42.6 23.0 198.1
 PRO-170   HIS-171  8.8 8.5 9.6 13.4 125.9 120.4 -41.3
 HIS-171   PRO-172  7.4 7.6 -4.9 5.8 118.4 113.6 -6.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-236   MET-237  8.6 8.4 -11.1 -11.0 58.2 78.8 22.9
 MET-237   LEU-238  8.5 8.5 5.8 21.7 58.4 55.6 10.6
 LEU-238   ASN-239  7.1 6.5 -4.1 23.1 157.7 153.7 103.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees