B-Raf Proto-Oncogene Serine/threonine-Protein Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-481   VAL-482  12.4 12.2 -1.0 -8.3 68.6 68.7 -5.1
 VAL-482   LYS-483  9.4 9.3 10.5 -19.9 114.5 120.4 23.3
 LYS-483   MET-484  8.0 8.0 -22.2 -30.9 48.3 45.0 52.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-503   VAL-504  5.1 5.5 3.0 2.3 131.5 138.6 -11.2
 VAL-504   LEU-505  5.5 5.8 -8.3 -4.0 80.5 73.0 19.6
 LEU-505   ARG-506  3.3 3.2 -3.9 24.0 47.9 59.9 -30.3
 ARG-506   LYS-507  0.7 1.0 -41.1 14.9 24.4 15.4 93.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees