Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  SER-108   LEU-109  4.6 4.9 -16.5 4.5 55.9 58.6 34.4  LEU-109   GLY-110  1.6 2.2 7.4 17.5 51.6 51.0 66.0  GLY-110   ILE-111  3.1 3.4 -11.6 4.0 57.2 52.7 7.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-215   ASP-216  7.9 7.8 -0.4 1.2 45.8 44.2 5.9  ASP-216   SER-217  5.0 4.9 -3.8 6.3 108.1 107.7 33.0  SER-217   LYS-218  1.6 1.4 -6.4 -17.5 88.1 79.7 38.2  LYS-218   GLY-219  4.2 4.4 18.8 -2.3 61.1 46.5 46.2  GLY-219   TYR-220  6.6 7.0 7.5 0.4 64.6 65.9 -33.2  TYR-220   GLY-221  9.5 9.9 -2.5 4.0 69.4 68.6 7.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees