Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  SER-108   LEU-109  3.9 3.8 -3.6 0.9 49.5 50.1 3.7  LEU-109   GLY-110  0.8 1.2 -6.3 21.4 123.4 121.2 41.6  GLY-110   ILE-111  3.4 3.6 -12.4 -4.8 49.4 49.1 52.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-215   ASP-216  8.8 9.1 -3.7 5.1 33.7 31.7 1.4  ASP-216   SER-217  5.9 6.2 -1.8 -8.1 101.6 102.9 -3.0  SER-217   LYS-218  2.1 2.5 -2.8 -20.7 77.5 62.5 69.8  LYS-218   GLY-219  2.8 2.3 17.6 6.1 69.0 56.5 41.1  GLY-219   TYR-220  5.1 4.9 16.2 -1.2 78.4 80.5 -4.3  TYR-220   GLY-221  8.4 8.4 12.1 -8.5 118.4 121.1 -14.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  TRP-254   TRP-255  9.7 9.8 8.7 -6.4 99.9 96.5 3.9  TRP-255   TYR-256  6.3 6.4 -5.4 -5.3 47.3 47.8 40.0  TYR-256   ASP-257  7.8 7.7 7.2 15.0 138.6 136.1 -72.1  ASP-257   LYS-258  10.8 10.8 -5.6 -16.6 46.1 24.3 106.2  LYS-258   GLY-259  8.9 9.0 14.7 11.9 100.4 94.4 -6.6  GLY-259   GLU-260  5.6 5.6 -13.6 13.0 10.9 15.2 2.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees