Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-85   GLY-86  5.3 4.5 122.3 -153.8 116.9 88.8 30.2
 GLY-86   PRO-87  2.4 2.7 47.8 6.4 94.7 115.8 -41.6
 PRO-87   GLU-88  5.2 5.7 -33.7 -10.3 36.7 54.5 141.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-185   LEU-186  11.6 12.3 -15.5 -21.1 28.8 28.5 110.1
 LEU-186   PRO-187  9.7 10.0 -13.1 5.0 56.8 71.1 7.7
 PRO-187   ALA-188  8.6 8.4 -14.5 7.4 102.2 100.9 -14.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees