Dual Specificity Mitogen-Activated Protein Kinase Kinase 6
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-81
LYS-82
7.5
7.2
-10.2
-27.2
97.1
80.9
-2.4
LYS-82
ARG-83
11.2
10.9
16.8
20.5
16.4
41.0
57.0
ARG-83
ILE-84
12.9
13.8
18.5
64.1
92.2
103.9
-22.5
VAL-81
LYS-82
2.7
4.9
-10.2
-27.2
75.1
67.7
30.8
LYS-82
ARG-83
4.4
6.2
16.8
20.5
125.3
117.0
-51.4
ARG-83
ILE-84
5.5
6.8
18.5
64.1
84.0
68.2
28.8
ILE-84
ARG-85
9.1
9.1
-3.1
-0.3
72.7
39.9
-2.1
VAL-81
LYS-82
7.5
7.2
-10.2
-27.2
97.1
80.9
-2.4
LYS-82
ARG-83
11.2
10.9
16.8
20.5
16.4
41.0
57.0
ARG-83
ILE-84
12.9
13.8
18.5
64.1
92.2
103.9
-22.5
VAL-81
LYS-82
2.7
4.9
-10.2
-27.2
75.1
67.7
30.8
LYS-82
ARG-83
4.4
6.2
16.8
20.5
125.3
117.0
-51.4
ARG-83
ILE-84
5.5
6.8
18.5
64.1
84.0
68.2
28.8
ILE-84
ARG-85
9.1
9.1
-3.1
-0.3
72.7
39.9
-2.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ASP-108
CYS-109
3.8
1.8
50.1
-74.8
114.0
132.8
18.6
CYS-109
PRO-110
3.3
1.7
3.4
16.8
65.0
74.2
19.9
PRO-110
PHE-111
7.1
5.3
-11.3
9.8
118.9
113.4
-8.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees