Major Prion Protein

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  VAL-189   THR-190  9.5 9.1 43.4 -5.1 105.4 118.2 -9.2  THR-190   THR-191  7.7 7.0 168.3 -9.4 62.2 86.0 28.1  THR-191   THR-192  5.1 3.4 172.8 -71.3 108.9 72.2 9.9  THR-192   THR-193  5.1 2.1 -108.9 -71.4 35.8 83.9 -67.6  THR-193   LYS-194  3.4 3.1 177.8 40.3 77.8 14.4 103.5  LYS-194   GLY-195  0.9 4.3 -76.8 -123.0 117.0 119.4 -44.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees