Liver Alcohol Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-175   PHE-176  4.5 4.4 7.2 7.8 93.3 91.3 -2.9
 PHE-176   SER-177  1.3 1.2 -8.8 5.9 31.4 29.5 20.6
 SER-177   THR-178  3.0 3.1 5.1 -7.5 138.7 141.1 -5.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 SER-289   VAL-290  10.9 11.0 3.0 3.5 94.1 90.2 -31.9
 VAL-290   ILE-291  7.6 7.7 -3.8 4.6 62.6 65.1 44.0
 ILE-291   VAL-292  8.0 8.3 12.0 -28.9 122.5 122.6 210.9
 VAL-292   GLY-293  6.2 6.9 -1.7 96.4 88.1 74.4 -172.1
 GLY-293   VAL-294  8.8 10.3 -17.0 65.4 115.6 128.7 462.0
 VAL-294   PRO-295  12.1 12.1 -9.8 -16.3 73.9 103.7 121.6
 PRO-295   PRO-296  15.1 15.1 13.2 5.6 38.6 93.6 64.8
 PRO-296   ASP-297  16.2 18.7 140.5 71.0 62.5 31.2 -1430.5
 ASP-297   SER-298  19.3 19.4 109.2 131.6 66.4 38.3 1926.7
 SER-298   GLN-299  17.8 19.9 -128.4 -1.8 160.1 97.9 -867.1
 GLN-299   ASN-300  19.5 20.3 -30.1 -39.8 114.7 117.4 -277.2
 ASN-300   LEU-301  18.5 19.0 -1.6 9.7 67.3 72.7 -60.4
 LEU-301   SER-302  18.4 18.6 9.3 -17.5 34.3 29.7 -69.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 TRP-314   LYS-315  8.9 9.1 10.6 -15.3 94.6 93.9 -2.5
 LYS-315   GLY-316  5.5 5.7 5.7 2.5 136.6 142.1 46.2
 GLY-316   ALA-317  4.2 4.8 13.2 0.6 103.8 102.0 -48.8
 ALA-317   ILE-318  2.5 2.8 -5.3 16.0 48.3 43.0 -92.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLU-366   SER-367  14.7 15.6 -127.4 39.9 126.4 87.1 -284.3
 SER-367   ILE-368  12.1 12.2 63.2 -37.8 137.3 145.2 -308.5
 ILE-368   ARG-369  9.1 9.4 -25.5 35.6 71.5 81.6 -59.7
 ARG-369   THR-370  8.0 8.0 1.3 3.8 36.3 30.1 75.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees