Cyclin-Dependent Kinase 6

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-17   GLU-18  17.7 18.0 -5.5 -19.3 53.8 62.9 124.9
 GLU-18   ILE-19  18.2 18.5 -14.2 49.4 32.1 18.8 -249.7
 ILE-19   GLY-20  16.2 17.0 -42.3 7.3 45.8 50.5 191.3
 GLY-20   GLU-21  17.1 18.8 36.4 -28.8 65.9 75.2 68.8
 GLU-21   GLY-22  19.1 19.6 38.5 -74.0 126.8 149.5 188.2
 GLY-22   ALA-23  17.6 19.5 42.9 -5.0 83.4 77.1 61.3
 ALA-23   TYR-24  20.3 19.2 46.9 -68.8 18.1 34.4 -203.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-75   VAL-76  4.6 4.6 0.8 -6.5 78.3 82.1 -7.6
 VAL-76   VAL-77  4.3 4.2 8.9 -11.0 29.9 31.9 -40.4
 VAL-77   ARG-78  2.7 2.6 18.8 -3.6 42.1 33.1 73.1
 ARG-78   LEU-79  4.0 3.3 -9.9 -5.8 55.8 62.6 44.3
 ARG-78   LEU-79  4.0 3.3 -9.9 -5.8 55.8 62.6 44.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-78   LEU-79  4.0 3.3 -9.9 -5.8 55.8 62.6 44.3
 ARG-78   LEU-79  4.0 3.3 -9.9 -5.8 55.8 62.6 44.3
 LEU-79   PHE-80  6.4 5.9 5.2 -15.3 162.9 162.3 95.4
 PHE-80   ASP-81  4.6 4.5 -9.2 18.2 43.7 49.3 -50.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-96   VAL-97  11.4 11.2 -18.7 24.3 88.8 88.9 -24.2
 VAL-97   PHE-98  8.1 7.8 25.8 -28.1 126.4 130.7 13.7
 PHE-98   GLU-99  5.8 5.2 12.1 -6.7 91.6 91.0 101.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees