Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-536   MET-537  7.9 9.2 -9.5 6.6 151.2 150.9 12.6
 MET-537   ILE-538  6.5 7.8 -8.1 5.5 88.2 88.1 0.1
 ILE-538   GLY-539  3.7 4.9 -4.1 12.9 70.7 71.2 -7.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-544   ILE-545  4.2 4.6 29.5 -19.0 45.3 45.4 16.7
 ILE-545   ASN-546  2.2 2.4 -22.1 3.5 65.4 59.1 52.0
 ASN-546   LEU-547  5.0 5.4 19.6 -6.6 72.4 70.7 50.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-561   GLU-562  5.9 6.2 2.9 -11.1 139.7 137.0 36.8
 GLU-562   TYR-563  4.6 5.0 2.0 -9.7 128.1 129.4 21.3
 TYR-563   ALA-564  2.6 3.1 9.3 -10.8 95.3 98.5 6.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-639   ALA-640  5.1 5.1 6.2 10.4 84.8 82.9 8.3
 ALA-640   ASP-641  3.8 3.3 -21.0 -2.6 65.1 51.5 56.6
 ASP-641   PHE-642  6.4 5.2 -26.9 -5.3 5.2 15.6 166.9
 PHE-642   GLY-643  6.0 3.8 -30.3 -43.2 69.0 53.5 128.1
 GLY-643   LEU-644  9.7 5.1 37.9 28.6 141.2 87.6 -139.4
 LEU-644   ALA-645  10.7 8.5 73.1 117.8 138.8 153.5 -973.3
 ALA-645   ARG-646  7.3 9.6 -93.5 -1.0 35.7 60.5 430.9
 ARG-646   ASP-647  7.1 7.2 -49.2 -77.4 55.0 60.2 366.0
 ASP-647   ILE-648  4.8 4.8 -41.1 -3.7 27.2 15.0 204.6
 ILE-648   HIS-649  4.6 5.5 65.4 -115.6 126.5 112.2 112.1
 HIS-649   HIS-650  1.5 3.3 37.7 56.2 168.5 141.0 -469.4
 HIS-650   ILE-651  2.6 1.5 -15.1 -80.5 74.4 29.9 299.4
 ILE-651   ASP-652  5.9 3.5 -54.9 -147.0 104.0 94.2 175.6
 LYS-655   LYS-656  14.9 15.2 72.5 -70.1 55.2 33.4 -10.8
 LYS-656   THR-657  16.9 16.9 80.7 -15.6 117.7 94.7 -95.1
 THR-657   THR-658  19.4 20.4 -109.1 -24.6 128.4 109.1 -334.8
 THR-658   ASN-659  21.4 23.5 31.7 -176.2 56.3 3.5 971.2
 ASN-659   GLY-660  22.6 25.1 29.1 73.2 22.6 66.3 -1137.3
 GLY-660   ARG-661  21.9 23.4 47.6 113.3 59.3 50.9 460.0
 ARG-661   LEU-662  20.5 21.3 -61.0 -8.2 69.0 69.1 142.5
 LEU-662   PRO-663  18.9 19.1 9.9 -4.3 56.2 68.7 39.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees