Dipeptidyl-Peptidase 3

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 VAL-332   ALA-333  9.3 9.4 4.3 -15.9 105.0 104.1 10.1
 ALA-333   VAL-334  5.5 5.9 4.0 34.4 29.4 31.5 56.6
 VAL-334   VAL-335  4.4 4.4 -3.1 -15.4 96.4 89.0 14.8
 VAL-335   ASN-336  2.7 1.0 -10.8 6.5 82.2 93.5 2.5
 ASN-336   LYS-337  6.1 4.0 33.3 -24.3 38.1 52.6 1.6
 LYS-337   ALA-338  7.6 6.1 -31.5 19.2 80.8 65.2 -14.8
 ALA-338   MET-339  10.8 9.5 -4.4 -14.6 72.0 52.4 7.5
 MET-339   SER-340  9.3 8.6 28.3 -26.1 42.2 69.6 13.3
 SER-340   ALA-341  7.9 7.4 8.0 7.5 60.7 61.1 15.9
 ALA-341   LYS-342  11.2 10.5 10.3 -15.1 115.8 126.6 -2.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASP-372   PHE-373  12.5 10.5 69.4 -11.0 28.1 24.4 87.6
 PHE-373   THR-374  10.0 9.2 -7.9 2.8 74.2 86.4 4.7
 THR-374   SER-375  6.3 5.6 50.2 -3.7 30.3 26.1 75.9
 SER-375   LEU-376  3.9 3.7 -21.5 15.4 72.9 85.3 7.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 VAL-415   ALA-416  4.1 4.4 -84.8 -22.7 51.8 43.7 151.2
 ALA-416   TYR-417  3.6 3.3 148.5 -69.1 149.9 92.4 -84.9
 ARG-421   GLU-422  13.2 11.9 49.0 -15.8 154.9 145.3 -43.5
 GLU-422   LYS-423  11.7 10.3 -5.8 11.9 86.5 97.7 2.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLU-667   SER-668  1.7 4.4 -9.9 -41.6 48.7 64.9 32.1
 SER-668   ARG-669  2.7 4.7 -38.6 -9.3 20.9 31.9 67.7
 ARG-669   LYS-670  3.0 4.1 18.5 -7.5 96.7 99.6 -4.9
 LYS-670   LEU-671  3.3 3.9 19.8 -26.2 123.1 131.4 5.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees