Carboxyl-Terminal Src Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-68   GLU-69  10.0 10.2 17.8 -19.0 55.0 61.8 4.3
 GLU-69   GLY-70  9.4 9.2 -7.1 5.3 81.9 81.3 -4.2
 GLY-70   VAL-71  7.6 7.5 9.5 -16.7 151.2 149.7 60.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-76   LEU-77  14.8 14.5 -29.3 24.6 97.9 100.3 -22.9
 LEU-77   SER-78  11.0 10.7 13.0 -8.4 64.0 58.8 37.5
 SER-78   LEU-79  9.8 9.2 22.6 -24.4 57.8 58.9 1.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-171   VAL-172  13.5 13.0 25.3 -11.0 24.4 14.5 111.6
 VAL-172   MET-173  13.1 12.5 -25.7 44.2 108.6 115.8 95.5
 MET-173   GLU-174  16.1 15.4 59.9 -51.7 56.1 63.8 56.2
 GLU-174   GLY-175  16.9 17.2 -5.4 5.7 10.9 3.4 0.5
 GLU-174   GLY-175  16.9 17.2 -5.4 5.7 10.9 3.4 0.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-174   GLY-175  16.9 17.2 -5.4 5.7 10.9 3.4 0.5
 GLU-174   GLY-175  16.9 17.2 -5.4 5.7 10.9 3.4 0.5
 GLY-175   THR-176  17.1 16.8 -32.8 52.0 61.6 71.1 -26.7
 THR-176   VAL-177  13.6 13.2 3.7 -16.4 98.1 110.2 80.0
 VAL-177   ALA-178  11.1 10.9 -13.7 3.5 94.8 93.3 21.5
 ALA-178   ALA-179  7.5 7.4 -0.1 -6.8 30.9 30.9 53.2
 ALA-179   GLN-180  5.6 5.4 11.6 -5.6 86.9 83.0 -7.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-181   GLU-182  6.4 6.3 47.0 -28.7 13.0 26.6 142.7
 GLU-182   PHE-183  7.3 7.1 4.6 -9.6 57.1 49.1 -2.0
 PHE-183   TYR-184  4.4 4.4 22.5 -3.4 98.7 102.0 -22.9
 TYR-184   ARG-185  6.6 6.6 -0.1 -11.1 108.7 113.5 -44.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-234   ALA-235  7.1 7.2 6.9 -12.6 22.7 18.3 -39.4
 ALA-235   GLU-236  9.3 9.0 9.9 -1.6 45.7 46.7 63.7
 GLU-236   ALA-237  7.5 7.3 -10.1 13.8 86.7 89.3 9.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-248   VAL-249  4.6 4.5 0.4 2.6 47.3 45.9 10.1
 VAL-249   GLN-250  6.6 6.7 12.2 -11.9 55.6 52.3 -10.3
 GLN-250   LEU-251  5.2 5.4 1.9 7.6 9.6 6.4 84.1
 LEU-251   LEU-252  4.4 4.4 6.6 -9.4 105.8 108.9 35.3
 LEU-251   LEU-252  4.4 4.4 6.6 -9.4 105.8 108.9 35.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-251   LEU-252  4.4 4.4 6.6 -9.4 105.8 108.9 35.3
 LEU-251   LEU-252  4.4 4.4 6.6 -9.4 105.8 108.9 35.3
 LEU-252   GLY-253  7.2 7.1 -5.6 -3.1 26.4 28.0 61.4
 GLY-253   VAL-254  5.7 5.2 11.3 -3.7 122.1 123.8 -88.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-260   GLY-261  8.0 8.7 -25.4 15.2 26.8 27.7 94.4
 GLY-261   LEU-262  9.1 9.8 -26.8 14.3 43.4 45.7 64.0
 LEU-262   TYR-263  7.7 8.0 11.8 -7.3 145.4 150.7 -23.6
 TYR-263   ILE-264  8.2 8.2 -2.1 10.8 136.5 136.3 41.1
 TYR-263   ILE-264  8.2 8.2 -2.1 10.8 136.5 136.3 41.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-263   ILE-264  8.2 8.2 -2.1 10.8 136.5 136.3 41.1
 TYR-263   ILE-264  8.2 8.2 -2.1 10.8 136.5 136.3 41.1
 ILE-264   VAL-265  6.9 6.9 -6.4 9.7 120.6 116.5 10.3
 VAL-265   THR-266  8.4 8.3 14.0 -13.7 19.7 16.8 16.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees