Leukotriene A-4 Hydrolase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-304   VAL-305  3.7 3.7 3.4 -2.0 48.2 45.6 12.8
 VAL-305   ASN-306  0.4 0.6 13.9 -22.9 117.1 116.5 49.5
 ASN-306   VAL-307  3.5 4.0 12.4 -6.4 86.2 85.3 -4.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-312   GLY-313  10.1 9.8 -12.9 19.2 65.4 81.6 21.9
 GLY-313   GLY-314  7.7 6.6 2.2 26.1 62.8 45.1 119.6
 GLY-314   MET-315  7.6 7.6 6.5 10.5 73.0 72.8 -14.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-509   ALA-510  6.4 6.8 32.7 -35.6 78.0 86.3 -14.9
 ALA-510   ASP-511  3.2 3.3 36.8 -16.1 32.4 27.6 150.5
 ASP-511   ASN-512  3.3 3.6 -8.5 8.0 84.0 93.5 -14.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-594   ASN-595  11.2 10.9 0.6 -18.4 84.2 89.6 -23.1
 ASN-595   ALA-596  7.5 7.4 -10.6 3.8 81.5 83.1 -24.5
 ALA-596   GLU-597  7.1 7.6 7.3 0.1 147.8 144.3 -43.0
 GLU-597   VAL-598  5.5 5.7 -11.6 8.8 39.5 36.7 15.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees