Hiv-1 Protease (Bru Isolate)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-31   VAL-32  4.7 5.0 -6.5 -0.6 82.5 86.6 19.9
 VAL-32   LEU-33  2.7 2.6 10.9 -1.8 37.9 33.1 58.7
 LEU-33   GLU-34  1.4 1.6 3.1 -2.5 93.5 95.5 18.6
 GLU-34   GLU-35  4.9 5.2 9.7 -13.9 122.1 130.0 -35.0
 GLU-35   MET-36  7.7 7.8 -1.9 8.0 109.1 109.0 -29.3
 MET-36   SER-37  9.0 8.6 -3.3 18.5 24.9 26.4 -83.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-39   GLY-40  12.5 12.0 -12.0 0.4 51.2 48.2 26.0
 GLY-40   ARG-41  10.3 9.9 -9.3 18.5 38.0 47.3 2.6
 ARG-41   TRP-42  8.4 8.3 19.2 -21.6 73.9 72.8 19.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-58   TYR-59  1.1 1.0 24.2 -20.6 78.6 79.5 40.4
 TYR-59   ASP-60  4.1 3.9 -4.6 12.0 94.3 93.4 15.4
 ASP-60   GLN-61  6.1 6.0 -19.9 -5.8 73.9 66.0 120.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-71   ILE-72  13.7 13.5 4.5 -21.7 140.8 134.5 135.3
 ILE-72   GLY-73  12.4 12.4 -12.3 -8.2 73.0 53.1 29.0
 GLY-73   THR-74  9.4 9.5 25.5 1.9 101.8 91.2 -50.4
 THR-74   VAL-75  5.9 5.8 3.3 -14.3 33.5 31.9 -84.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-83   ILE-84  2.0 1.9 14.8 -15.5 91.0 85.4 -80.6
 ILE-84   ILE-85  4.7 4.5 18.2 1.5 61.8 52.1 82.4
 ILE-85   GLY-86  6.6 6.6 4.7 7.5 75.8 70.5 37.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees