Focal Adhesion Kinase 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-155   MET-156  9.2 9.5 5.7 -3.5 102.0 101.6 6.5
 MET-156   LEU-157  11.2 11.6 14.0 -28.5 45.2 46.4 -134.4
 LEU-157   GLU-158  12.8 13.3 22.4 25.8 81.0 77.2 108.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-167   ALA-168  12.2 12.3 5.0 -2.3 102.8 109.6 -19.9
 ALA-168   LEU-169  12.4 12.5 17.4 -9.7 44.6 44.0 54.5
 LEU-169   LYS-170  11.4 11.7 -4.3 1.6 92.7 95.4 -38.6
 LYS-170   LEU-171  8.2 8.3 3.7 0.4 43.2 41.6 29.0
 LYS-170   LEU-171  8.2 8.3 3.7 0.4 43.2 41.6 29.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-170   LEU-171  8.2 8.3 3.7 0.4 43.2 41.6 29.0
 LYS-170   LEU-171  8.2 8.3 3.7 0.4 43.2 41.6 29.0
 LEU-171   GLY-172  7.0 7.2 -1.9 -2.2 84.7 85.5 -3.7
 GLY-172   CYS-173  8.8 9.0 14.5 -12.7 133.3 135.2 -27.1
 CYS-173   LEU-174  7.1 7.4 -1.4 3.6 107.5 104.4 42.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-176   ARG-177  8.1 8.4 -3.1 6.9 60.5 63.8 -24.8
 ARG-177   ARG-178  5.7 6.1 -14.5 15.1 125.6 126.4 30.1
 ARG-178   SER-179  6.0 6.2 14.2 -11.3 76.5 77.9 -9.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-182   MET-183  13.0 13.0 -7.6 15.1 141.8 133.0 105.4
 MET-183   ARG-184  11.8 12.2 -154.4 113.5 133.3 137.1 -251.1
 ARG-184   GLY-185  10.1 9.5 -60.8 45.5 88.9 118.4 -15.4
 GLY-185   ASN-186  6.6 6.8 116.6 -78.5 64.2 23.9 289.2
 ASN-186   ALA-187  8.2 8.7 -46.7 -10.6 78.7 83.3 81.7
 ALA-187   LEU-188  11.6 12.2 72.8 -62.2 105.8 124.1 -9.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-190   LYS-191  15.5 15.4 -13.1 5.0 130.6 123.5 -81.0
 LYS-191   SER-192  18.5 18.5 32.8 -32.7 50.7 60.6 37.3
 SER-192   ASN-193  20.2 19.9 -9.7 8.4 145.2 149.7 3.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-223   ILE-224  14.4 14.3 10.3 -0.8 109.5 116.2 -49.8
 ILE-224   GLN-225  12.1 12.3 2.7 -2.4 43.2 48.0 0.9
 GLN-225   GLN-226  11.0 11.0 -9.4 6.4 110.6 110.9 2.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-228   ARG-229  6.4 6.5 4.5 -10.3 129.5 130.1 57.3
 ARG-229   GLN-230  4.5 4.5 24.9 -5.3 74.8 77.4 63.7
 GLN-230   PHE-231  3.8 3.6 -20.1 0.9 131.4 122.6 -146.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-233   LEU-234  3.8 4.0 -18.0 7.6 33.0 26.2 110.5
 LEU-234   ASN-235  4.2 4.2 -7.5 2.7 60.8 62.5 5.9
 ASN-235   ARG-236  7.0 6.9 4.2 -2.5 154.1 152.8 -10.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-238   SER-239  5.5 5.7 14.0 -3.3 81.6 90.1 10.9
 SER-239   ILE-240  1.9 2.2 2.1 -13.0 23.4 27.6 -136.1
 ILE-240   LEU-241  2.2 2.0 8.3 0.7 84.3 82.1 19.1
 LEU-241   LYS-242  5.1 5.0 8.0 -5.0 116.8 117.2 21.4
 LYS-242   PHE-243  4.7 4.6 -9.5 6.3 120.7 121.9 -1.2
 PHE-243   PHE-244  3.6 3.6 0.6 -1.9 48.0 46.1 32.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-253   ASP-254  8.2 8.2 16.0 -23.7 116.0 105.0 22.3
 ASP-254   LYS-255  9.5 9.9 13.4 -21.5 152.0 150.4 65.8
 LYS-255   GLU-256  11.2 11.3 -3.7 2.5 58.9 58.4 -0.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees