Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-638   ILE-639  11.8 11.5 -0.6 17.3 93.1 94.5 -1.6
 ILE-639   ALA-640  8.0 7.8 -2.4 16.8 21.9 27.0 -17.3
 ALA-640   ASP-641  6.2 6.2 -38.7 8.9 90.3 90.4 11.1
 ASP-641   PHE-642  3.6 3.0 -33.3 10.8 98.7 112.9 -7.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-660   ARG-661  13.6 17.8 -149.4 -16.2 86.9 41.9 -266.1
 ARG-661   LEU-662  11.7 14.7 82.2 51.1 113.4 70.8 -39.0
 LEU-662   PRO-663  9.1 13.2 -21.8 -6.5 31.8 89.6 27.6
 PRO-663   VAL-664  9.3 9.7 -140.4 7.9 34.2 54.1 128.0
 VAL-664   LYS-665  10.3 10.3 17.4 -8.6 138.2 147.0 -11.6
 LYS-665   TRP-666  8.8 9.0 -11.5 23.4 95.6 89.6 -0.1
 TRP-666   MET-667  5.3 5.4 6.1 -6.8 83.0 84.2 3.5
 MET-667   ALA-668  6.8 6.5 -12.6 24.5 29.3 34.3 -8.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees