Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  MET-107   SER-108  8.0 7.8 -1.8 -6.3 115.4 117.4 -13.8  SER-108   LEU-109  4.4 4.3 -14.3 3.9 44.2 43.4 40.2  LEU-109   GLY-110  1.4 1.3 8.3 18.2 61.7 64.9 61.1  GLY-110   ILE-111  2.9 3.1 -2.6 -8.4 44.1 42.5 30.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-215   ASP-216  8.3 8.8 -7.2 4.4 31.7 26.9 19.3  ASP-216   SER-217  5.6 6.2 -1.3 -2.8 96.4 95.9 9.0  SER-217   LYS-218  1.9 2.5 8.0 -29.5 102.3 113.7 46.6  LYS-218   GLY-219  3.3 2.9 13.4 7.2 74.3 61.2 26.1  GLY-219   TYR-220  5.6 5.4 17.5 -4.9 78.0 77.9 0.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees