Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-714   GLY-715  7.6 7.4 122.3 -141.1 108.7 80.5 -27.4  GLY-715   PRO-716  3.9 3.7 20.3 -4.4 100.8 109.4 -11.4  PRO-716   GLU-717  3.4 3.4 -75.0 41.2 32.7 18.9 164.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-817   PRO-818  7.0 7.0 2.6 -12.3 131.7 126.3 36.8  PRO-818   ALA-819  5.3 5.1 -12.7 6.6 107.1 100.2 -11.0  ALA-819   VAL-820  3.1 2.6 -8.2 10.0 80.6 61.0 -2.1  VAL-820   SER-821  0.7 0.6 -24.7 -3.9 82.6 78.2 60.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees