Metabotropic Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-185   PRO-186  3.9 4.0 6.4 -3.6 115.8 112.0 -29.6
 PRO-186   PRO-187  3.5 3.7 -3.5 4.9 31.3 30.5 -50.1
 PRO-187   ASP-188  3.6 3.9 3.6 -3.9 76.0 75.9 52.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-319   ALA-320  2.8 3.0 4.3 -9.0 160.7 158.5 52.6
 ALA-320   SER-321  1.4 1.5 -10.3 18.1 82.0 83.6 -53.2
 SER-321   TYR-322  4.0 4.2 -15.2 11.2 29.2 25.5 62.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-441   ARG-442  11.9 12.0 -2.0 2.7 56.6 58.5 -7.0
 ARG-442   PHE-443  13.1 13.1 -6.4 -4.4 36.9 37.2 74.7
 PHE-443   ASP-444  12.3 12.3 -2.4 13.2 81.8 75.4 -39.5
 ASP-444   ARG-445  13.0 13.2 -10.1 -16.4 31.0 38.5 341.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-447   ASP-448  11.2 11.2 -23.8 19.8 63.2 55.7 30.0
 ASP-448   GLY-449  8.1 8.4 -9.1 -1.5 2.2 6.1 121.5
 GLY-449   ILE-450  6.8 7.2 -4.1 -12.3 71.0 70.2 12.8
 ILE-450   GLY-451  6.6 7.1 1.6 5.9 84.6 70.9 20.3
 ILE-450   GLY-451  6.6 7.1 1.6 5.9 84.6 70.9 20.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-450   GLY-451  6.6 7.1 1.6 5.9 84.6 70.9 20.3
 ILE-450   GLY-451  6.6 7.1 1.6 5.9 84.6 70.9 20.3
 GLY-451   ARG-452  5.6 5.8 17.2 -3.9 25.6 18.2 135.7
 ARG-452   TYR-453  4.2 4.0 -10.3 0.9 86.0 85.6 5.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees