Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASP-208   THR-209  5.7 6.2 36.5 -24.0 83.7 85.0 13.1
 THR-209   LEU-210  4.0 3.9 8.2 0.2 66.9 59.6 0.1
 LEU-210   GLN-211  1.0 1.4 26.6 -9.2 18.4 12.6 220.5
 GLN-211   ALA-212  3.1 3.2 -5.4 15.2 126.4 110.8 19.5
 ALA-212   ARG-213  3.5 3.9 -3.6 -14.2 93.3 97.6 14.4
 ARG-213   ALA-214  2.7 2.6 -18.1 17.0 141.1 146.1 -14.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 HIS-231   THR-232  14.3 14.4 15.8 -22.9 80.3 85.3 33.8
 THR-232   GLU-233  16.7 16.9 13.0 1.5 31.6 25.9 125.4
 GLU-233   GLY-234  19.4 19.4 12.0 3.8 42.4 48.9 79.6
 GLY-234   ASN-235  19.1 18.7 -33.4 17.3 67.2 63.6 129.1
 GLY-234   ASN-235  19.1 18.7 -33.4 17.3 67.2 63.6 129.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-234   ASN-235  19.1 18.7 -33.4 17.3 67.2 63.6 129.1
 GLY-234   ASN-235  19.1 18.7 -33.4 17.3 67.2 63.6 129.1
 ASN-235   TYR-236  16.5 15.8 3.4 6.2 64.6 57.7 6.2
 TYR-236   GLY-237  13.9 13.5 -11.2 13.2 117.0 126.6 27.2
 GLY-237   GLU-238  13.2 13.6 9.1 -15.6 124.2 114.0 67.0
 GLU-238   SER-239  14.7 14.6 -11.0 7.1 44.4 54.1 -13.6
 SER-239   GLY-240  12.1 11.8 5.9 6.6 68.9 57.0 63.5
 GLY-240   MET-241  9.0 9.2 -2.6 -9.6 114.4 119.1 -72.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-316   SER-317  7.4 7.2 24.5 -8.8 39.3 38.0 93.6
 SER-317   ASP-318  7.4 7.5 4.1 -11.1 90.5 98.2 12.1
 ASP-318   GLY-319  9.8 9.9 7.6 -6.9 94.3 96.8 40.3
 GLY-319   TRP-320  12.5 12.8 25.6 -26.5 155.7 161.6 3.1
 TRP-320   ALA-321  12.3 12.1 -0.7 -16.6 91.2 87.4 -29.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ILE-340   LYS-341  6.3 6.4 38.3 -41.3 72.0 70.4 50.9
 LYS-341   LEU-342  9.8 9.6 29.8 -9.2 29.9 37.3 172.0
 LEU-342   GLN-343  10.3 10.8 13.6 5.1 92.3 106.3 -76.4
 GLN-343   SER-344  12.9 13.2 42.0 -24.1 41.5 60.8 72.2
 SER-344   PRO-345  15.9 16.7 -24.2 14.8 64.3 80.0 68.6
 PRO-345   GLU-346  18.9 19.3 -44.1 29.2 113.0 103.5 -61.8
 GLU-346   VAL-347  22.4 22.8 -18.4 13.8 135.6 137.8 -4.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-477   ARG-478  7.4 7.2 -2.6 2.4 134.8 142.4 -26.4
 ARG-478   TYR-479  9.4 9.4 -7.5 8.5 143.3 135.4 69.6
 TYR-479   ASP-480  8.1 8.4 17.2 -3.2 25.1 27.6 87.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-498   THR-499  9.4 9.6 18.0 -3.5 26.2 28.0 124.5
 THR-499   TRP-500  9.2 9.3 7.2 -2.6 47.7 56.7 -54.3
 TRP-500   HIS-501  7.3 7.3 5.2 7.3 35.8 37.1 70.3
 HIS-501   GLU-502  9.8 10.0 8.7 -10.0 32.6 35.2 7.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees