Toll-Like Receptor 3

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASN-520   ILE-521  32.7 32.6 -11.2 8.3 43.8 33.4 -8.4
 ILE-521   ASN-522  30.9 31.5 -0.4 -8.3 66.2 71.8 494.1
 ASN-522   ASP-523  29.2 29.6 -3.4 -11.1 12.5 13.0 962.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 MET-525   LEU-526  27.1 27.3 -1.4 0.1 143.8 143.5 67.2
 LEU-526   GLU-527  27.4 27.7 -9.2 10.2 139.1 139.8 6.3
 GLU-527   GLY-528  25.3 25.7 9.3 -9.8 58.6 61.8 30.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASN-540   ASN-541  39.4 39.5 5.0 -2.8 67.0 65.7 87.6
 ASN-541   LEU-542  39.8 39.9 1.8 -8.9 114.8 115.2 -119.5
 LEU-542   ALA-543  39.0 39.2 2.2 -5.3 95.8 95.4 -33.5
 ALA-543   ARG-544  42.3 42.4 1.4 1.6 85.9 87.4 98.3
 ARG-544   LEU-545  41.0 41.0 0.4 0.6 136.1 138.8 -91.1
 LEU-545   TRP-546  38.5 38.5 -2.3 -1.9 35.7 38.8 153.6
 TRP-546   LYS-547  41.3 41.3 -3.6 10.7 103.4 105.3 -109.9
 LYS-547   HIS-548  43.7 43.7 4.1 -10.5 100.0 104.9 -86.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-561   SER-562  31.5 31.8 1.5 -11.7 30.6 31.5 0.8
 SER-562   HIS-563  32.0 32.5 0.5 7.5 70.0 69.8 140.7
 HIS-563   LEU-564  32.4 32.8 -3.2 3.9 50.6 47.7 -7.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASN-572   GLY-573  43.4 43.6 9.9 1.4 62.6 63.0 -20.2
 GLY-573   PHE-574  46.2 46.1 -17.7 13.0 62.6 56.5 286.7
 PHE-574   ASP-575  46.0 45.9 -9.0 4.7 88.3 90.7 -145.1
 ASP-575   GLU-576  48.8 48.8 22.4 -15.8 124.6 122.5 62.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LYS-583   ASP-584  38.7 38.8 20.2 -3.2 49.3 51.2 827.2
 ASP-584   LEU-585  35.5 35.6 -3.0 -2.1 103.1 104.9 -189.0
 LEU-585   PHE-586  37.1 37.3 3.3 -5.1 32.9 32.4 96.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-593   GLY-594  47.0 46.9 -7.7 11.5 127.1 126.6 74.0
 GLY-594   LEU-595  49.9 49.8 -1.0 -7.3 167.0 167.0 -493.1
 LEU-595   ASN-596  50.4 50.4 2.1 8.0 66.2 68.5 366.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 VAL-610   SER-611  43.5 43.2 -6.1 7.0 100.9 99.9 -23.3
 SER-611   LEU-612  42.8 42.6 -1.5 -6.0 49.3 51.0 -124.0
 LEU-612   LYS-613  45.2 45.0 -0.6 11.6 107.3 109.7 166.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASN-616   LEU-617  50.7 50.3 -8.3 8.4 133.3 138.0 208.9
 LEU-617   GLN-618  51.9 51.7 -4.2 8.7 128.9 127.6 -101.9
 GLN-618   LYS-619  54.3 54.1 -6.5 8.8 165.4 161.9 17.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASN-636   LEU-637  50.6 49.6 -28.1 -1.5 46.0 55.0 522.5
 LEU-637   THR-638  51.2 50.9 -15.1 6.3 103.5 111.8 97.4
 THR-638   GLU-639  52.1 52.1 35.4 -21.5 141.4 146.2 -620.5
 GLU-639   LEU-640  53.3 53.0 -13.5 7.3 55.0 53.0 366.1
 LEU-640   ASP-641  54.4 54.2 4.9 -0.1 147.1 144.1 -57.8
 ASP-641   MET-642  55.1 54.8 -7.3 13.9 53.6 54.1 -35.9
 MET-642   ARG-643  56.4 56.1 2.4 20.7 128.3 124.4 -660.5
 ARG-643   PHE-644  58.9 58.7 160.2 -176.0 158.4 148.2 326.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees